The world's first medical retreat centre dedicated to Dr Thomas Seyfried 's groundbreaking Press-Pulse Protocol : A non-toxic, mitochondrial metabolic approach to managing cancer and other chronic diseases. Combining peer-reviewed science with holistic and functional medicine all in a tranquil setting ripe for  healing.       "No tumour cell can survive in the absence of glucose and glutamine ".     The Press-Pulse Protocol  targets the unique metabolic vulnerabilities of cancer with precision. Since the body converts protein into g lucose and glutamine, dietary restriction of these nutrients alone isn't enough. The  approach blocks cancer's access to these critical fuel sources in synergy with other non-toxic therapies offered at our clinic.  The result? A powerful strategy not just for managing cancer and chronic disease but boosting mitochondrial metabolic function, overall health and lifespan. What is Press-Pulse? ...

Essential Healing Prep

Foundational Lifestyle Interventions

  • Prioritize sleep in complete darkness (7-9 hrs/night): Promotes melatonin production, mitophagy, and DNA repair. Allows for cleansing pathways in brain, gut etc.
  • Prioritize A.M. sunlight exposure: Regulates circadian rhythms, activates melatonin production in mitochondria, supports mitochondrial function 
  • Prioritize daily movement: (esp. aerobic and resistance): Increases mitochondrial biogenesis and glucose regulation
  • Time-Restricted Eating (6-8 hr eating window): Enhances autophagy and metabolic flexibility 
  • Minimize EMF and blue light exposure at night: Protects melatonin and mitochondrial signaling (communication)

Therapeutic Nutrition

  • Low-glycemic or ketogenic diet reduces glucose fermentation in BRCA1-deficient cells
  • High-antioxidant foods (e.g., berries, greens, crucifers, sulfur rich, turmeric to quench Free Radicals and protect mitochondria
  • High-healthy fat, moderate protein, low carb: Favours fat-based fuel (mitochondrial preference)
  • Avoid synthetic vitamins like folic acid that are difficult  to break down, build up and become toxic. Especially important with MTHFR or BRCA-related folate handing issues.

Targeted Supplementation:

Supplement:

  • Methylfolate  + Methyl B12: Dose Range: As per labs/MTHFR status: Supports DNA methylation and detoxification
  • CoQ10 (ubiquinol form) 100-300 mg/day: Supports electron transport and energy production (OXPHOS)
  • PQQ 10-20 mg/day: Promotes mitochondrial biogenesis 
  • Alpha-Lipoic Acid (ALA): 300-600 mg/day: Regenerates other antioxidants and supports OXPHOS
  • Acetyl-L-Carnitine; 500-2,000 mg/day: Transports fatty acids into mitochondria
  • Melatonin 1-10 mg nightly: Enhances mitochondrial antioxidant capacity and mitophagy. Note: Endogenous production is best: Sleep and rise with the sun. Morning sunlight exposure and sleep i complete darkness
  • NAC/Glycine/Selenium: doses per protocol: Supports Glutathione support for redox balance 

Important: Dosages adjusted to individual health status, goals, lab results, age and medical conditions

Advanced Mitochondrial + metabolic Support

  • Berberine/Metformin: Activate AMPK, lowers glucose, and mimics calorie restriction
  • MitoQ or SkQ1: Targeted mitochondrial antioxidants
  • IV Vitamin C Therapy: Pro-oxidant effect against metabolically inflexible cells
  • Press-Pulse Strategy: Cyclical metabolic stress with fasting, ketones, and intermittent therapy "pulses"

Monitoring and Customization

Labs: 

  • Methylation profile.
  • CRP
  • Glutathione levels
  • Fasting insulin & glucose
  • Homocysteine
  • Nutrient panels
  • Genetic screening: MTHFR, COMT, SOD2, GST variants
  • Ongoing review of energy levels, mood, inflammation makers, metabolic flexibility 
This protocol is not a one-size-fits-all approach. Its a launchpad. At Oxizona we work with you to tailor and fine-tune every element of your care—so your genetics become a guidepost, not a destiny

Clinical Action Plan

Essential Healing Prep
Medical Retreats
Reset Weeks
HBOT
IV Drips
Ozone Therapy
Red Light Therapy
HIIT & Resistance
Cold plunging
Hyperthermia
Testing & Labs



Resources:
Frontiers | Cancer as a mitochondrial metabolic disease